SCHEMBL465381

SCHEMBL465381

CC(c1ccccc1)(c1ccccc1)c1ccc(Nc2ccc(C(C)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.58
ESR2 Q92731 3/20 0.58
ALDH1A1 P00352 7/20 0.55
HSD17B10 Q99714 4/20 0.55
ALOX12 P18054 4/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
ALOX15 P16050 2/20 0.55
TSHR P16473 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MAPK1 P28482 2/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
PTGS2 P35354 1/20 0.55
HTR2B P41595 1/20 0.55
HPGD P15428 4/20 0.50
NR3C2 P08235 2/20 0.46
CYP3A4 P08684 5/20 0.45
LMNA P02545 1/20 0.45
THRB P10828 1/20 0.45
RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15960965 0.92 HPGD (0.65) ESR1ESR2ALDH1A1HSD17B10ALOX12
SCHEMBL10951232 0.89 HPGD (0.68) ESR1ESR2ALDH1A1HSD17B10ALOX12
SCHEMBL158574 0.86 NR3C2 (0.60) ESR1ESR2ALDH1A1HSD17B10ALOX12
Diphenylamine SCHEMBL8206764 0.86 ESR1 (0.77) ESR1ESR2ALDH1A1HSD17B10ALOX12
SCHEMBL5887915 0.84 ESR1 (0.75) ESR1ESR2ALDH1A1ALOX15TSHR
SCHEMBL1576428 0.84 ALDH1A1 (0.59) ESR1ESR2ALDH1A1HSD17B10ALOX12
SCHEMBL8207410 0.84 ESR1 (0.67) ESR1ESR2ALDH1A1HSD17B10L3MBTL1
SCHEMBL8335012 0.82 ESR1 (0.70) ESR1ESR2ALDH1A1ALOX15TSHR
SCHEMBL430941 0.82 ESR1 (0.70) ESR1ESR2ALDH1A1ALOX15TSHR
SCHEMBL8626323 0.81 ALDH1A1 (0.62) ESR1ESR2ALDH1A1HSD17B10ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271235-B1 POLYPROPYLENE STABILIZED AGAINST OXIDATIVE DEGRADATION WITH MIXTURES OF ARALKYL-SUBSTITUTED DIARYLAMINES AND STERICALLY HINDERED PHENOLS UNIROYAL CHEMICAL COMPANY, Inc. (US) 1993-09-08 EP claimed
EP-4127062-B1 HEAT-AGING RESISTANT POLYAMIDE MOLDING COMPOSITIONS BASF SE (DE) 2024-05-08 EP disclosed
US-20230183476-A1 Acid Resistant Polyoxymethylene Composition and Articles Made Therewith CELANESE INTERNATIONAL CORPORATION 2023-06-15 US disclosed
WO-2023107679-A1 ACID RESISTANT POLYOXYMETHYLENE COMPOSITION AND ARTICLES MADE THEREWITH CELANESE INTERNATIONAL CORPORATION (US) 2023-06-15 WO disclosed
US-20230129664-A1 HEAT-AGING RESISTANT POLYAMIDE MOLDING COMPOSITIONS BASF SE (DE) 2023-04-27 US disclosed
WO-2022128171-A1 THERMOPLASTIC MOLDING COMPOSITION HAVING GOOD MECHANICAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2022-06-23 WO disclosed
EP-4015550-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
US-9765208-B2 Composite wheel for a vehicle E I DU PONT DE NEMOURS AND COMPANY (US) 2017-09-19 US disclosed
US-9752006-B2 Polyamide resin composition and molded article ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
EP-2307480-B1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS DU PONT (US) 2016-08-17 EP disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0509282-B1 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF AG (DE) 1996-07-24 EP disclosed
EP-0586985-A1 Stabilized Polyamide/Polyphenylene ether mouldings BASF Aktiengesellschaft (DE) 1994-03-16 EP disclosed
EP-0274200-B1 Polyolefins stabilized against oxidative degradation with mixtures of aralkyl-substituted diarylamines and sterically hindered phosphites UNIROYAL CHEM CO INC (US) 1994-02-02 EP disclosed
EP-0271235-B1 POLYPROPYLENE STABILIZED AGAINST OXIDATIVE DEGRADATION WITH MIXTURES OF ARALKYL-SUBSTITUTED DIARYLAMINES AND STERICALLY HINDERED PHENOLS UNIROYAL CHEMICAL COMPANY, Inc. (US) 1993-09-08 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
EP-0274200-A2 Polyolefins stabilized against oxidative degradation with mixtures of aralkyl-substituted diarylamines and sterically hindered phosphites UNIROYAL CHEMICAL COMPANY, Inc. (US) 1988-07-13 EP disclosed
EP-0260651-A2 Process for the preparation of a composition of parabutylated and octylated, ortho-ethylated diphenylamines The B.F. GOODRICH Company (US) 1988-03-23 EP disclosed
US-4704219-A Novel composition of para-butylated and octylated, ortho-ethylated diphenylamines THE B. F. GOODRICH COMPANY 1987-11-03 US disclosed