Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15960965 | 0.91 | HPGD (0.65) | ESR1ESR2HPGDALDH1A1L3MBTL1 | |
| Diphenylamine SCHEMBL8206764 | 0.90 | ESR1 (0.77) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL10951232 | 0.89 | HPGD (0.68) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL822977 | 0.89 | ESR1 (0.83) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL465381 | 0.84 | ESR1 (0.58) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL8211337 | 0.83 | ESR2 (0.61) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL8031149 | 0.82 | ESR1 (1.00) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL27277 | 0.82 | ESR1 (1.00) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL3143096 | 0.82 | ESR2 (0.67) | ESR1ESR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL13815221 | 0.82 | ESR2 (0.67) | ESR1ESR2HPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093784-A | (CO)POLYCARBONATE CONTAINING DIARYLAMINOPHENYL-SUBSTITUTED BISPHENOL UNITS; DURABILITY, HEAT RESISTANCE, RADIATION TRANSPARENCY | RICOH COMPANY, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |