SCHEMBL15965349

SCHEMBL15965349

CN(C)c1cccc(OCCC[SiH3])c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.53
MTNR1A P48039 9/20 0.46
MTNR1B P49286 9/20 0.46
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
FAAH O00519 1/20 0.43
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7455570 0.87 APP (0.60) APPMTNR1AMTNR1BNOS1NOS2
SCHEMBL7239002 0.84 APP (0.54) APPMTNR1AMTNR1BNOS1NOS2
SCHEMBL7022072 0.84 FAAH (0.56) APPMTNR1AMTNR1BFAAHKMT2A
SCHEMBL595463 0.83 APP (0.53) APPMTNR1AMTNR1BFAAHCHRNB2
SCHEMBL5957100 0.83 MTNR1A (0.53) APPMTNR1AMTNR1BNOS1NOS2
SCHEMBL1428483 0.83 KDM4E (0.56) APPMTNR1AMTNR1BCHRNB2CHRNA4
SCHEMBL10660855 0.83 TSHR (0.58) APPMTNR1AMTNR1BFAAH
SCHEMBL8807486 0.83 APP (0.53) APPMTNR1AMTNR1BNOS1NOS2
SCHEMBL9911816 0.82 APP (0.55) APPMTNR1AMTNR1BNOS1NOS2
SCHEMBL10339364 0.82 APP (0.55) APPMTNR1AMTNR1BNOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315670-B2 Composition for forming resist underlayer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-19 US disclosed
US-20140235796-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-21 US disclosed