SCHEMBL595463

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL594625	0.91	APP (0.54)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL7455570	0.87	APP (0.60)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL7239002	0.84	APP (0.54)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL7022072	0.84	FAAH (0.56)	APPMTNR1AMTNR1BFAAHKMT2A
	SCHEMBL21835116	0.83	APP (0.50)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL30879982	0.83	APP (0.50)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL5957100	0.83	MTNR1A (0.53)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL10660855	0.83	TSHR (0.58)	APPMTNR1AMTNR1BFAAHTSHR
	SCHEMBL15965349	0.83	APP (0.53)	APPMTNR1AMTNR1BFAAHCHRNB2
	SCHEMBL1428483	0.83	KDM4E (0.56)	APPMTNR1AMTNR1BCHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.