Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15965466 | 1.00 | ESR1 (0.41) | ESR1ESR2L3MBTL1MAPTTDP1 | |
| SCHEMBL15965467 | 0.96 | ESR1 (0.44) | ESR1ESR2L3MBTL1MAPTTDP1 | |
| SCHEMBL31099332 | 0.86 | ESR1 (0.41) | ESR1ESR2L3MBTL1MAPTTDP1 | |
| SCHEMBL22829515 | 0.86 | ESR1 (0.41) | ESR1ESR2L3MBTL1MAPTTDP1 | |
| SCHEMBL29317741 | 0.85 | ESR1 (0.52) | ESR1ESR2L3MBTL1MAPTAR | |
| SCHEMBL19954856 | 0.84 | ALDH1A1 (0.43) | ESR1ESR2MAPTTDP1AR | |
| SCHEMBL991964 | 0.83 | L3MBTL1 (0.39) | L3MBTL1MAPTTDP1SMN1; SMN2MEN1 | |
| SCHEMBL22338093 | 0.83 | ADRB2 (0.47) | ESR1ESR2L3MBTL1MAPTAR | |
| SCHEMBL21829163 | 0.81 | ESR1 (0.37) | ESR1ESR2MAPTTDP1ADRB2 | |
| SCHEMBL29831627 | 0.81 | ESR1 (0.37) | ESR1ESR2MAPTTDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |