Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966182 | 0.90 | ALDH1A1 (0.33) | PDK2ALDH1A1HTTF10MAPT | |
| SCHEMBL15965471 | 0.83 | PDK2 (0.35) | PDK2ALDH1A1MAPTIDO1TP53 | |
| SCHEMBL15966204 | 0.83 | PTPN11 (0.40) | PDK2ALDH1A1HTTKMT2A | |
| SCHEMBL15966202 | 0.82 | MAPT (0.33) | PDK2ALDH1A1HTTF10MAPT | |
| SCHEMBL15965474 | 0.81 | HTR1A (0.35) | PDK2ALDH1A1HTTMAPTLMNA | |
| SCHEMBL15965473 | 0.81 | HTR1A (0.35) | PDK2ALDH1A1HTTMAPTLMNA | |
| SCHEMBL15966203 | 0.72 | PTPN11 (0.41) | ALDH1A1HTTKMT2A | |
| SCHEMBL15965468 | 0.72 | L3MBTL1 (0.35) | PDK2ALDH1A1MAPT | |
| SCHEMBL15965469 | 0.70 | HTR1A (0.36) | ALDH1A1HTTMAPTLMNAKMT2A | |
| SCHEMBL15965470 | 0.70 | HTR1A (0.36) | ALDH1A1HTTMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |