Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228933 | 0.84 | S1PR1 (0.58) | S1PR1CETPMAOBACACBALDH1A1 | |
| SCHEMBL14797100 | 0.81 | S1PR1 (0.61) | S1PR1CETPMAOBACACBALDH1A1 | |
| SCHEMBL2222592 | 0.79 | S1PR1 (0.81) | S1PR1CETPMAOBACACBDHODH | |
| SCHEMBL2225306 | 0.79 | S1PR1 (0.54) | S1PR1ALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL15966895 | 0.77 | S1PR1 (0.54) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2222684 | 0.76 | S1PR1 (0.48) | S1PR1APPKMT2ATP53MAPT | |
| SCHEMBL2222401 | 0.73 | S1PR1 (0.49) | S1PR1ALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL2224650 | 0.73 | S1PR1 (0.58) | S1PR1ALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL2224142 | 0.72 | S1PR1 (0.51) | S1PR1CETPALDH1A1USP2CYP1A2 | |
| SCHEMBL14796967 | 0.72 | S1PR1 (0.62) | S1PR1CETPACACBDHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040544-B2 | 2,5-substituted oxazolopyrimidine derivatives | SANOFI (FR) | 2015-05-26 | — | — | US | claimed |
| EP-2523963-B1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES AS EDG-1 AGONISTS | SANOFI SA (FR) | 2014-08-27 | — | — | EP | disclosed |