Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 6/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CEPT1 | Q9Y6K0 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228824 | 0.84 | S1PR1 (0.42) | S1PR1MAPTLMNARXFP1APP | |
| SCHEMBL2225375 | 0.84 | S1PR1 (0.44) | S1PR1MAPTLMNARXFP1APP | |
| SCHEMBL2222186 | 0.84 | S1PR1 (0.48) | S1PR1MAPTLMNARXFP1APP | |
| SCHEMBL2222684 | 0.82 | S1PR1 (0.48) | S1PR1MAPTLMNARXFP1APP | |
| SCHEMBL2225593 | 0.81 | S1PR1 (0.52) | S1PR1MAPTLMNARXFP1APP | |
| SCHEMBL15966917 | 0.81 | MAPK14 (0.43) | S1PR1BRD4 | |
| SCHEMBL14797019 | 0.80 | S1PR1 (0.56) | S1PR1MAPTLMNARXFP1CEPT1 | |
| SCHEMBL2224059 | 0.78 | S1PR1 (0.51) | S1PR1MAPTLMNARXFP1APP | |
| SCHEMBL2225216 | 0.77 | S1PR1 (0.69) | S1PR1PTPN1MAPTLMNARXFP1 | |
| SCHEMBL2224473 | 0.77 | NPC1 (0.40) | S1PR1PTPN2PTPN1PTPN5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040544-B2 | 2,5-substituted oxazolopyrimidine derivatives | SANOFI (FR) | 2015-05-26 | — | — | US | claimed |
| EP-2523963-B1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES AS EDG-1 AGONISTS | SANOFI SA (FR) | 2014-08-27 | — | — | EP | disclosed |