Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
| ▸ | CEPT1 | Q9Y6K0 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223599 | 0.92 | S1PR1 (0.47) | S1PR1MAPTLMNARXFP1CEPT1 | |
| SCHEMBL2225559 | 0.92 | S1PR1 (0.49) | S1PR1MAPTLMNARXFP1SGMS2 | |
| SCHEMBL2222292 | 0.92 | S1PR1 (0.44) | S1PR1 | |
| SCHEMBL2224919 | 0.91 | S1PR1 (0.49) | S1PR1MAPTRXFP1SGMS2CEPT1 | |
| SCHEMBL2222071 | 0.89 | S1PR1 (0.44) | S1PR1MAPTLMNARXFP1TP53 | |
| SCHEMBL2223727 | 0.89 | S1PR1 (0.47) | S1PR1MAPTLMNARXFP1TP53 | |
| SCHEMBL2222684 | 0.89 | S1PR1 (0.48) | S1PR1MAPTLMNARXFP1SGMS2 | |
| SCHEMBL2222588 | 0.89 | S1PR1 (0.52) | S1PR1MAPTLMNARXFP1CEPT1 | |
| SCHEMBL2223699 | 0.88 | S1PR1 (0.45) | S1PR1RXFP1CEPT1TP53THRB | |
| SCHEMBL2225593 | 0.88 | S1PR1 (0.52) | S1PR1MAPTLMNARXFP1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | claimed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | claimed |
| EP-2523960-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086080-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |