Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773452 | 0.76 | TOP2A (0.44) | BCL2L1IRAK4KCNQ3KCNQ2 | |
| SCHEMBL760138 | 0.75 | MLYCD (0.43) | BCL2L1NLRP3TTKKCNQ3KCNQ2 | |
| SCHEMBL1091526 | 0.64 | KCNQ3 (0.47) | BCL2L1KCNQ3KCNQ2 | |
| SCHEMBL11916155 | 0.64 | HTR1A (0.41) | IRAK4 | |
| SCHEMBL16068790 | 0.64 | ALDH1A1 (0.45) | KCNQ3KCNQ2 | |
| SCHEMBL3773454 | 0.64 | MEN1 (0.35) | IRAK4 | |
| SCHEMBL5443635 | 0.63 | BCL2L1 (0.65) | BCL2L1IRAK4 | |
| SCHEMBL5146842 | 0.62 | BCL2L1 (0.54) | BCL2L1 | |
| SCHEMBL4322471 | 0.62 | TSHR (0.42) | KCNQ3KCNQ2 | |
| SCHEMBL9835945 | 0.61 | KCNQ3 (0.38) | IRAK4KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |