Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711123 | 0.92 | KDM4E (0.34) | CACNA1H | |
| SCHEMBL5505987 | 0.80 | SIGMAR1 (0.36) | — | |
| SCHEMBL708613 | 0.77 | GNAI3 (0.33) | CACNA1H | |
| SCHEMBL711458 | 0.76 | CACNA1H (0.33) | CACNA1H | |
| SCHEMBL15967367 | 0.76 | CYP2C19 (0.39) | CACNA1H | |
| SCHEMBL712560 | 0.76 | GNAI3 (0.38) | CACNA1H | |
| SCHEMBL708330 | 0.75 | CACNA1H (0.32) | CACNA1H | |
| SCHEMBL710575 | 0.75 | GNAI3 (0.40) | CACNA1H | |
| SCHEMBL15967265 | 0.72 | — | — | |
| SCHEMBL711902 | 0.70 | CHRM5 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |