Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909672 | 0.71 | SHBG (0.38) | EPHX1SHBG | |
| SCHEMBL13219744 | 0.63 | ADH1B (0.34) | EPHX1 | |
| SCHEMBL9566239 | 0.63 | SHBG (0.38) | SHBG | |
| SCHEMBL9821146 | 0.62 | CHRM5 (0.33) | — | |
| SCHEMBL7135996 | 0.62 | SHBG (0.41) | EPHX1SHBGTP53 | |
| SCHEMBL16321558 | 0.62 | TP53 (0.34) | EPHX1SHBGTP53 | |
| SCHEMBL2178276 | 0.62 | SCN1A (0.33) | — | |
| SCHEMBL1327001 | 0.61 | — | — | |
| SCHEMBL7876056 | 0.61 | SCN1A (0.31) | — | |
| SCHEMBL8384899 | 0.61 | SCN1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243414-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | JAPAN TOBACCO INC. (JP) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243414-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | CETP, NPC1L1, LCAT | EPHX1 1274/4885SHBG 1745/4885TP53 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.