Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15970366 | 0.92 | CYP19A1 (0.56) | CYP19A1CYP11B2CYP26A1PDE4D | |
| SCHEMBL15969572 | 0.86 | CYP19A1 (0.49) | CYP19A1CYP26A1MEN1GLAKMT2A | |
| SCHEMBL15969573 | 0.80 | CYP19A1 (0.42) | CYP19A1CYP11B2CYP26A1MEN1GLA | |
| SCHEMBL8272615 | 0.67 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP26A1 | |
| SCHEMBL15969815 | 0.67 | MTNR1A (0.39) | CYP19A1MEN1GLAKMT2AGAA | |
| SCHEMBL20809838 | 0.66 | CYP19A1 (0.68) | CYP19A1CYP26A1MEN1GLAKMT2A | |
| SCHEMBL8243133 | 0.64 | CYP19A1 (0.66) | CYP19A1PDE4D | |
| SCHEMBL12306070 | 0.63 | CYP19A1 (0.65) | CYP19A1PDE4D | |
| SCHEMBL8462840 | 0.62 | CYP19A1 (0.60) | CYP19A1CYP11B2CYP26A1MEN1KMT2A | |
| SCHEMBL6378154 | 0.62 | CYP19A1 (1.00) | CYP19A1CYP26A1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243335-A1 | SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243335-A1 | SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC1, H1-3 | CYP19A1 739/4885CYP11B2 848/4885CYP26A1 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.