Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71158 | 0.86 | TRPC6 (0.48) | CNR2 | |
| SCHEMBL30439691 | 0.86 | TRPC6 (0.54) | CNR2 | |
| SCHEMBL21045633 | 0.86 | TRPC6 (0.54) | CNR2 | |
| SCHEMBL15968688 | 0.85 | KMO (0.51) | CNR2 | |
| SCHEMBL21045686 | 0.81 | TRPC6 (0.55) | CNR2 | |
| SCHEMBL15968458 | 0.80 | MAPK1 (0.41) | — | |
| SCHEMBL15777276 | 0.80 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL1861841 | 0.77 | PDE4B (0.50) | — | |
| Hydrochloric Acid SCHEMBL31160603 | 0.76 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL21045688 | 0.75 | TRPC6 (0.56) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133129-B2 | Bicyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-09-15 | — | — | US | disclosed |
| EP-2772485-A1 | BICYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-20140243310-A1 | BICYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243310-A1 | BICYCLIC COMPOUND | BICRA, NR3C2, CYP11B2 | CNR2 741/4885CNR1 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.