Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA6 | P23280 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | CA5A | P35218 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CA3 | P07451 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermidine SCHEMBL1286935 | 0.85 | CA12 (0.64) | CA12CA6CA7CA9CA14 | |
| Guanidine SCHEMBL28483885 | 0.85 | CA12 (0.67) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL9814189 | 0.82 | CA12 (0.69) | CA12CA6CA7CA9CA14 | |
| Biguanide SCHEMBL8719175 | 0.82 | MAPT (0.36) | LMNATDP1CYP1A2CYP2C19TSHR | |
| SCHEMBL2489631 | 0.76 | CA12 (0.71) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5314937 | 0.74 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL15381 | 0.74 | — | — | |
| Biguanide SCHEMBL18255803 | 0.74 | MAPK1 (0.31) | — | |
| Biguanide SCHEMBL8039 | 0.74 | — | — | |
| Thiourea SCHEMBL3345993 | 0.73 | CA12 (0.67) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190142857-A1 | METHODS | TECREA LIMITED (GB) | 2019-05-16 | — | — | US | claimed |
| US-20160089393-A1 | COMPOSITION AND METHODS FOR COMBATING ANTIBACTERIAL RESISTANT BACTERIA | BLUEBERRY THERAPEUTICS LIMITED (GB) | 2016-03-31 | — | — | US | claimed |
| US-20140242097-A1 | METHODS | THE ROYAL VETERINARY COLLEGE (GB) | 2014-08-28 | — | — | US | claimed |
| US-20190142857-A1 | METHODS | TECREA LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10238683-B2 | Methods for promoting entry of an agent into a cell | THE ROYAL VETERINARY COLLEGE (GB) | 2019-03-26 | — | — | US | disclosed |
| US-20160089393-A1 | COMPOSITION AND METHODS FOR COMBATING ANTIBACTERIAL RESISTANT BACTERIA | BLUEBERRY THERAPEUTICS LIMITED (GB) | 2016-03-31 | — | — | US | disclosed |
| US-20140242097-A1 | METHODS | THE ROYAL VETERINARY COLLEGE (GB) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142857-A1 | METHODS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NUP210, PUF60 | CA12 392/4885CA6 548/4885CA7 533/4885 |
| US-20140242097-A1 | METHODS | NUP210, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PUF60 | CA12 488/4885CA6 602/4885CA7 551/4885 |
| US-10238683-B2 | Methods for promoting entry of an agent into a cell | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NUP210, CCR10 | CA12 375/4885CA6 449/4885CA7 516/4885 |
| US-20160089393-A1 | COMPOSITION AND METHODS FOR COMBATING ANTIBACTERIAL RESISTANT BACTERIA | BPGM, PGM2, PMM2 | CA12 1594/4885CA6 2155/4885CA7 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.