Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072189 | 0.78 | CTSA (0.30) | CTSAACHE | |
| SCHEMBL818254 | 0.77 | LMNA (0.39) | TDP1CYP2C19LMNATP53 | |
| SCHEMBL24801628 | 0.75 | TP53 (0.35) | TP53 | |
| SCHEMBL11197693 | 0.73 | CTSA (0.39) | CTSAACHEPOLBKDM4ETDP1 | |
| SCHEMBL4050 | 0.71 | POLB (0.44) | POLBKDM4ETDP1ALDH1A1GAA | |
| SCHEMBL10832923 | 0.70 | CTSA (0.46) | CTSAACHEPOLBKDM4ETDP1 | |
| SCHEMBL15439047 | 0.70 | KDM4E (0.34) | CTSAACHEPOLBKDM4ETDP1 | |
| SCHEMBL6016751 | 0.70 | HMGCR (0.39) | CTSAACHEPOLBKDM4ETDP1 | |
| SCHEMBL575230 | 0.69 | CTSA (0.50) | CTSAACHEPOLBKDM4EALDH1A1 | |
| SCHEMBL10910619 | 0.69 | CTSA (0.50) | CTSAACHEPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014129874-A1 | PIPER AMIDE-BASED COMPOUND AS BOMBESIN RECEPTOR SUBTYPE 3 | 서울대학교산학협력단 (KR) | 2014-08-28 | — | — | WO | disclosed |