SCHEMBL1597072

SCHEMBL1597072

Oc1c(Cl)cc(C(CCCC(c2cc(Cl)c(O)c(Cl)c2)c2cc(Cl)c(O)c(Cl)c2)c2cc(Cl)c(O)c(Cl)c2)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.56
ALOX15 P16050 3/20 0.56
ALOX12 P18054 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HIF1A Q16665 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
CYP2C9 P11712 2/20 0.56
TSHR P16473 6/20 0.44
TTR P02766 3/20 0.44
CYP3A4 P08684 3/20 0.44
RECQL P46063 3/20 0.44
ALDH1A1 P00352 2/20 0.44
THRB P10828 3/20 0.41
KIF11 P52732 1/20 0.38
HPGD P15428 4/20 0.36
MAPK1 P28482 3/20 0.36
ESR1 P03372 3/20 0.35
MEN1 O00255 2/20 0.35
EGFR P00533 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1596641 0.91 HSD17B10 (0.61) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL6555161 0.83 HSD17B10 (0.52) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL1595357 0.81 HSD17B10 (0.61) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL2415957 0.77 HSD17B10 (0.56) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL1597822 0.77 ESR2 (0.47) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL5189783 0.74 HSD17B10 (0.42) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL1595906 0.73 TSHR (0.44) HSD17B10ALOX15ALOX12HIF1ACYP2C19
SCHEMBL1597151 0.73 CA1 (0.44) CYP1A2CYP2C9TTRCYP3A4ALDH1A1
SCHEMBL10456511 0.72 ALOX15 (0.41) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL9808035 0.72 HSD17B10 (0.50) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1780224-B1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2015-02-18 EP disclosed
US-8710165-B2 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
US-20110152388-A1 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2011-06-23 US disclosed
US-7919570-B2 narrowly dispersed; controlled molecular weight; ionic conductivity, shape stability; battery adhesive or binder; 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane or pentaerythritol reacted with bromoisobutyroyl bromide for core; living radical polymerization of acrylate or a styrene at halogen atoms as the arms NIPPON SODA CO., LTD. (JP) 2011-04-05 US disclosed
US-7601784-B2 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane is used to molecular alignment, chemical stabilization, heat resist, flexiable and modification of the polyether having hydrogen bond sites; for waste water treatments, energy transducers, conductors NIPPON SODA CO., LTD. (JP) 2009-10-13 US disclosed
US-20080214685-A1 Multibrached Polymer and Method for Producing the Same NIPPON SODA CO., LTD. (JP) 2008-09-04 US disclosed
EP-1792947-A1 Molecular compound comprising polymer having hydrogen bond as component compound NIPPON SODA CO., LTD. (JP) 2007-06-06 EP disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed
US-20050228167-A1 Molecular compounds containing polymers having hydrogen bond sites as the constituent compounds NIPPON SODA CO., LTD. (JP) 2005-10-13 US disclosed
US-20020193528-A1 Molecular compound comprising polymer having hydrogen bond as component compound NIPPON SODA CO., LTD. (JP) 2002-12-19 US disclosed
EP-1241230-A1 MOLECULAR COMPOUND COMPRISING POLYMER HAVING HYDROGEN BOND AS COMPONENT COMPOUND NIPPON SODA CO., LTD. (JP) 2002-09-18 EP disclosed
EP-0589044-B1 NOVEL INCLUSION COMPOUND COMPRISING TETRAKISPHENOL AS HOST NIPPON SODA CO (JP) 1996-10-23 EP disclosed
US-5364977-A Chemical stabilization and powder processing NIPPON SODA CO., LTD. (JP) 1994-11-15 US disclosed
EP-0589044-A1 NOVEL INCLUSION COMPOUND COMPRISING TETRAKISPHENOL AS HOST NIPPON SODA CO., LTD. (JP) 1994-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193528-A1 Molecular compound comprising polymer having hydrogen bond as component compound PIEZO1, PARN, PARG HSD17B10 3191/4885ALOX15 2840/4885ALOX12 2116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.