Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383154 | 0.82 | CA1 (0.44) | CYP1A2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL647632 | 0.80 | HSD17B10 (0.64) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| SCHEMBL21397880 | 0.78 | HSD17B10 (0.61) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| SCHEMBL28358911 | 0.76 | HSD17B10 (0.59) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| SCHEMBL27791013 | 0.76 | HSD17B10 (0.59) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| SCHEMBL1480310 | 0.76 | HSD17B10 (0.59) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| Methyl Isonicotinate SCHEMBL180574 | 0.76 | CYP1A2 (0.60) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| Methyl Isonicotinate SCHEMBL820082 | 0.76 | CYP1A2 (0.60) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| SCHEMBL1615795 | 0.76 | HSD17B10 (0.59) | HSD17B10NAPRTCYP1A2CYP2C19LMNA | |
| SCHEMBL27418916 | 0.76 | HSD17B10 (0.59) | HSD17B10NAPRTCYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695162-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-02-02 | — | — | US | disclosed |
| US-9475803-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150376176-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| WO-2014130513-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376176-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1454/4885NAPRT 638/4885CYP1A2 4319/4885 |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1295/4885NAPRT 590/4885CYP1A2 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.