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Sugi Predict / Compounds / Phosphoric Acid

Phosphoric Acid

Phosphoric Acid

SCHEMBL15974124

CCC(O)OC(O)CC.O=P(O)(O)O

nearest known ligand 0.72

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.72
▸ LAP3 P28838 1/20 0.40
▸ FDPS P14324 3/20 0.35
▸ MMP1 P03956 2/20 0.34
▸ MMP2 P08253 2/20 0.34
▸ METAP1 P53582 1/20 0.34
▸ PGK1 P00558 1/20 0.34
▸ PGK2 P07205 1/20 0.34
▸ CA12 O43570 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ MMP8 P22894 1/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ MMP3 P08254 1/20 0.33
▸ SMPD1 P17405 3/20 0.31
▸ PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716479 0.85 — —
SCHEMBL93793 0.85 — —
SCHEMBL10947112 0.82 TSHR (0.81) TSHR
Phosphoric Acid SCHEMBL21408828 0.79 TSHR (0.43) TSHRLAP3FDPSMMP1MMP2
Trimethylammonium SCHEMBL10699104 0.77 TSHR (0.81) TSHR
Ethylene Glycol SCHEMBL904502 0.77 TSHR (0.81) TSHR
SCHEMBL7152553 0.76 TSHR (0.46) TSHRLAP3FDPSMMP1MMP2
SCHEMBL29582 0.76 — —
Phosphoric Acid SCHEMBL1360058 0.76 LAP3 (0.48) TSHRLAP3FDPSMMP1MMP2
Phosphoric Acid SCHEMBL8842709 0.76 LAP3 (0.48) TSHRLAP3FDPSMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105473185-B A moisturizing composition that can be applied to wet skin in the form of an oil-in-water emulsion; moisturizing nursing method 莱雅公司 2020-04-28 — — CN claimed
EP-3038713-B1 MOISTURIZING COMPOSITION WHICH MAY BE APPLIED TO WET SKIN IN THE FORM OF AN OIL-IN-WATER EMULSION; MOISTURIZING CARE PROCESS OREAL (FR) 2020-03-11 — — EP claimed
EP-3038713-A1 MOISTURIZING COMPOSITION WHICH MAY BE APPLIED TO WET SKIN IN THE FORM OF AN OIL-IN-WATER EMULSION; MOISTURIZING CARE PROCESS L'OREAL (FR) 2016-07-06 — — EP claimed
CN-105473185-A A moisturizing composition that can be applied to wet skin in the form of an oil-in-water emulsion; moisturizing nursing method L'OREAL S A 2016-04-06 — — CN claimed
WO-2015028381-A1 MOISTURIZING COMPOSITION WHICH MAY BE APPLIED TO WET SKIN IN THE FORM OF AN OIL-IN-WATER EMULSION; MOISTURIZING CARE PROCESS L'OREAL (FR) 2015-03-05 — — WO claimed
EP-2958631-B1 DISPENSING DEVICE COMPRISING AN AQUEOUS COMPOSITION IN GEL OR THICK CREAM FORM OREAL (FR) 2022-02-09 — — EP disclosed
US-20210402048-A1 THIN-FILM VEHICLES THAT STABILIZE HIGHLY REACTIVE ACTIVE INGREDIENTS L'OREAL (FR) 2021-12-30 — — US disclosed
CN-113766906-A Cosmetic composition in the form of a soft solid comprising a hydrophobic powder selected from silica aerogel and polylactic acid, starch and a UV filter system 欧莱雅 2021-12-07 — — CN disclosed
US-11135336-B2 Thin-film vehicles that stabilize highly reactive active ingredients L'OREAL (FR) 2021-10-05 — — US disclosed
WO-2021067098-A1 THIN-FILM VEHICLES THAT STABILIZE HIGHLY REACTIVE ACTIVE INGREDIENTS L'OREAL (FR) 2021-04-08 — — WO disclosed
US-20210093747-A1 THIN-FILM VEHICLES THAT STABILIZE HIGHLY REACTIVE ACTIVE INGREDIENTS L'OREAL (FR) 2021-04-01 — — US disclosed
WO-2020220099-A1 COSMETIC COMPOSITIONS IN A SOFT-SOLID FORMAT COMPRISING A HYDROPHOBIC POWDER SELECTED FROM SILICA AEROGEL AND POLYLACTIC ACID, STARCH AND AN UV-FILTER SYSTEM L'OREAL (FR) 2020-11-05 — — WO disclosed
EP-2958544-A2 SOFT SOLID OIL-IN-WATER EMULSION COMPRISING A MIXTURE OF NONIONIC SURFACTANTS, A WATER-SOLUBLE POLYSACCHARIDE AND A WAX COMPRISING AT LEAST ONE ESTER L'Oréal (FR) 2015-12-30 — — EP disclosed
EP-2958545-A2 OIL-IN-WATER EMULSION COMPRISING AT LEAST ONE SPECIFIC MIXTURE OF NONIONIC SURFACTANTS, A WAX COMPRISING AT LEAST ONE ESTER AND A WATER-SOLUBLE POLYSACCHARIDE L'Oréal (FR) 2015-12-30 — — EP disclosed
EP-2958631-A1 DISPENSING DEVICE COMPRISING AN AQUEOUS COMPOSITION IN GEL OR THICK CREAM FORM L'Oréal (FR) 2015-12-30 — — EP disclosed
WO-2015071298-A2 FOAMING COMPOSITION COMPRISING AT LEAST ONE GLYCINATE TYPE SURFACTANT L'OREAL (FR) 2015-05-21 — — WO disclosed
WO-2015028381-A1 MOISTURIZING COMPOSITION WHICH MAY BE APPLIED TO WET SKIN IN THE FORM OF AN OIL-IN-WATER EMULSION; MOISTURIZING CARE PROCESS L'OREAL (FR) 2015-03-05 — — WO disclosed
WO-2014128061-A1 DISPENSING DEVICE COMPRISING AN AQUEOUS COMPOSITION IN GEL OR THICK CREAM FORM L'OREAL (FR) 2014-08-28 — — WO disclosed
WO-2014128060-A2 OIL-IN-WATER EMULSION COMPRISING AT LEAST ONE SPECIFIC MIXTURE OF NONIONIC SURFACTANTS, A WAX COMPRISING AT LEAST ONE ESTER AND A WATER-SOLUBLE POLYSACCHARIDE L'OREAL (FR) 2014-08-28 — — WO disclosed
WO-2014128058-A2 SOFT SOLID OIL-IN-WATER EMULSION COMPRISING A MIXTURE OF NONIONIC SURFACTANTS, A WATER-SOLUBLE POLYSACCHARIDE AND A WAX COMPRISING AT LEAST ONE ESTER L'OREAL (FR) 2014-08-28 — — WO disclosed