Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975508 | 0.87 | FOLH1 (0.46) | TGM2SIRT2SIRT1FOLH1CPB1 | |
| SCHEMBL277854 | 0.86 | SIRT2 (0.48) | SIRT2SIRT1SIRT3 | |
| SCHEMBL12410205 | 0.84 | SIRT1 (0.49) | SIRT2SIRT1SIRT3 | |
| SCHEMBL13026641 | 0.84 | FOLH1 (0.47) | TGM2SIRT2SIRT1FOLH1CPB1 | |
| SCHEMBL25176589 | 0.84 | KMT2A (0.45) | TGM2SIRT2SIRT1SIRT3 | |
| SCHEMBL25176590 | 0.84 | KMT2A (0.45) | TGM2SIRT2SIRT1SIRT3 | |
| SCHEMBL11955643 | 0.84 | SIRT2 (0.43) | TGM2SIRT2SIRT1CPB1CPB2 | |
| SCHEMBL11955678 | 0.82 | SIRT2 (0.42) | TGM2SIRT2SIRT1FOLH1SIRT3 | |
| SCHEMBL2607891 | 0.82 | SIRT1 (0.44) | SIRT2SIRT1CPB1CPB2SIRT3 | |
| SCHEMBL12583936 | 0.82 | SIRT1 (0.47) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815227-B2 | Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom | NEKTAR THERAPEUTICS (US) | 2014-08-26 | — | — | US | disclosed |