Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | TGM2 | P21980 | 9/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975505 | 0.87 | TGM2 (0.48) | FOLH1TGM2CPB1CPB2SIRT2 | |
| SCHEMBL13026641 | 0.82 | FOLH1 (0.47) | FOLH1TGM2CPB1CPB2SIRT2 | |
| SCHEMBL18907025 | 0.81 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157462 | 0.81 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157482 | 0.81 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907028 | 0.81 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157463 | 0.81 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL13901982 | 0.80 | CPB1 (0.46) | FOLH1TGM2CPB1CPB2SIRT1 | |
| SCHEMBL13511507 | 0.80 | TGM2 (0.41) | FOLH1TGM2CPB1CPB2SIRT2 | |
| SCHEMBL8641871 | 0.79 | FOLH1 (0.69) | FOLH1CPB1CPB2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815227-B2 | Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom | NEKTAR THERAPEUTICS (US) | 2014-08-26 | — | — | US | disclosed |