Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15363522 | 0.89 | NPC1 (0.35) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL10278858 | 0.89 | NPC1 (0.37) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL4969785 | 0.89 | NPC1 (0.37) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL10236114 | 0.88 | ALDH1A1 (0.34) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL15363512 | 0.88 | LMNA (0.35) | NPC1RAB9AHTTDGAT1ALDH1A1 | |
| SCHEMBL15975697 | 0.85 | ALDH1A1 (0.38) | NPC1RAB9AHTTDGAT1ALDH1A1 | |
| SCHEMBL15975668 | 0.83 | NPC1 (0.35) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL18627105 | 0.83 | NPC1 (0.36) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL15363310 | 0.83 | NPC1 (0.36) | NPC1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL15975689 | 0.83 | NPC1 (0.37) | NPC1RAB9AHTTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9655365-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9655365-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9591857-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-14 | — | — | US | disclosed |
| US-9591857-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-14 | — | — | US | disclosed |
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-9282739-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-03-15 | — | — | US | disclosed |
| US-20150335022-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2015-11-26 | — | — | US | disclosed |
| US-8937083-B2 | Pesticidal compositions and processes related thereto | DowAgroSciences, LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8937083-B2 | Pesticidal compositions and processes related thereto | DowAgroSciences, LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8901153-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901153-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335022-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885HTT 4384/4885 |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885HTT 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.