SCHEMBL15975698

SCHEMBL15975698

[2H]C(C)(CSC)C(=O)N(C)c1cn(-c2cccnc2)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.32
MAT2A P31153 2/20 0.31
FAAH O00519 1/20 0.31
KCNH2 Q12809 1/20 0.31
GRM1 Q13255 2/20 0.31
DGAT1 O75907 1/20 0.31
GRM5 P41594 1/20 0.31
TLR8 Q9NR97 1/20 0.31
PRMT5 O14744 1/20 0.30
GAA P10253 1/20 0.30
MAP3K5 Q99683 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14904649 0.90 LMNA (0.35) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL15975691 0.88 ALDH1A1 (0.33) ALDH1A1NPC1RAB9AMAPK1MAT2A
SCHEMBL15975671 0.86 LMNA (0.33) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL15363412 0.86 MAPK1 (0.36) ALDH1A1NPC1RAB9AMAPK1MAT2A
SCHEMBL29901222 0.85 LMNA (0.34) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL15356835 0.85 LMNA (0.34) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL15975679 0.85 ALDH1A1 (0.32) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL4967929 0.85 MAPK1 (0.36) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL4969070 0.85 LMNA (0.34) ALDH1A1NPC1RAB9AMAPK1LMNA
SCHEMBL15356947 0.84 MAPK1 (0.35) ALDH1A1NPC1RAB9AMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708288-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-18 US disclosed
US-9655365-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-05-23 US disclosed
US-9591857-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-03-14 US disclosed
US-9422278-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-08-23 US disclosed
US-9282739-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-03-15 US disclosed
US-8937083-B2 Pesticidal compositions and processes related thereto DowAgroSciences, LLC (US) 2015-01-20 US disclosed
US-8901153-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-12-02 US disclosed
US-8815271-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-08-26 US disclosed