Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261813 | 0.87 | KDM4E (0.47) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL22100019 | 0.83 | MAT2A (0.55) | ALDH1A1TSHRMAT2AKDM4EATM | |
| SCHEMBL16644617 | 0.82 | PDE4B (0.44) | ALDH1A1CYP2C19TSHRMAT2AFEN1 | |
| SCHEMBL11978691 | 0.82 | CYP2C19 (0.49) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL17349274 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL17124118 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL17349188 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL5021401 | 0.78 | KDM4E (0.61) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL20161001 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP2C19TSHRFEN1KDM4E | |
| SCHEMBL13932200 | 0.77 | KDM4E (0.41) | ALDH1A1CYP2C19TSHRFEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786242-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE, DISPLAY APPARATUS AND LIGHTING APPARATUS | KONICA MINOLTA HOLDINGS INC (JP) | 2014-08-27 | — | — | EP | disclosed |