SCHEMBL22100019

SCHEMBL22100019

Cc1ccc2c3ccccc3n(-c3ccccc3)c2n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 2/20 0.55
KDM4E B2RXH2 2/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAPK8 P45983 3/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
MAPK9 P45984 2/20 0.44
HKDC1 Q2TB90 1/20 0.43
PGR P06401 3/20 0.41
HSD17B10 Q99714 2/20 0.38
MAPK10 P53779 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 2/20 0.38
RXFP1 Q9HBX9 1/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20313300 0.86 MAT2A (0.43) MAT2AKDM4EATML3MBTL1MAPK1
SCHEMBL15977170 0.83 ALDH1A1 (0.44) MAT2AKDM4EATML3MBTL1HSD17B10
SCHEMBL18546821 0.80 KDM4E (0.55) MAT2AKDM4EATML3MBTL1MAPK8
SCHEMBL18941667 0.80 L3MBTL1 (0.55) MAT2AKDM4EATML3MBTL1MAPK8
SCHEMBL17109976 0.77 GPR3 (0.54) KDM4EL3MBTL1HTTHKDC1HSD17B10
SCHEMBL17051458 0.77 KDM4E (0.55) MAT2AKDM4EATML3MBTL1MAPK8
SCHEMBL21085498 0.76 KDM4E (0.46) MAT2AKDM4EATML3MBTL1MAPK8
SCHEMBL25058968 0.76 HSD17B10 (0.42) MAT2AKDM4EATML3MBTL1MAPK1
SCHEMBL20368022 0.75 KDM4E (0.53) KDM4EATML3MBTL1MAPK8MAPK1
SCHEMBL20313309 0.75 SMN1; SMN2 (0.49) MAT2AKDM4EL3MBTL1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-20210367162-A1 HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM MAT2A 4786/4885KDM4E 807/4885ATM 2886/4885
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 MAT2A 4533/4885KDM4E 2665/4885ATM 3936/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 MAT2A 4533/4885KDM4E 2665/4885ATM 3936/4885
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES RPS4X, MLX, RPS4Y1 MAT2A 4717/4885KDM4E 1801/4885ATM 2153/4885
US-11834459-B2 Host materials for electroluminescent devices RPS4X, MLX, RPS4Y1 MAT2A 4717/4885KDM4E 1801/4885ATM 2153/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 MAT2A 4533/4885KDM4E 2665/4885ATM 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.