Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD5 | P21918 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475925 | 0.96 | ALDH1A1 (0.40) | LMNAALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL8740164 | 0.76 | ALDH1A1 (0.45) | LMNAALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL26019884 | 0.74 | ALDH1A1 (0.38) | LMNAALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL31348347 | 0.71 | CYP4F2 (0.37) | LMNAALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL1009291 | 0.71 | CYP4F2 (0.43) | LMNAALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL1366880 | 0.71 | CYP4F2 (0.51) | ALDH1A1CYP4F2CYP4A11RXRARXRB | |
| SCHEMBL4046867 | 0.71 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL158142 | 0.71 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL989607 | 0.70 | MCHR1 (0.46) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL31299364 | 0.70 | RXRA (0.36) | LMNAALDH1A1POLBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476680-B1 | (1-Azinone)-Substituted Pyridoindoles | ALBANY MOLECULAR RES INC (US) | 2014-08-27 | — | — | EP | disclosed |