SCHEMBL15977609

SCHEMBL15977609

c1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)c3cc(-c4ccc(-c5cccnc5)cn4)ccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.43
CYP11B1 P15538 4/20 0.36
CYP11B2 P19099 3/20 0.36
CYP2A6 P11509 3/20 0.33
CYP3A4 P08684 2/20 0.33
DHODH Q02127 1/20 0.33
PIK3CA P42336 1/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
CCNT1 O60563 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CDK9 P50750 1/20 0.33
LMNA P02545 1/20 0.33
RAF1 P04049 1/20 0.33
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
PDPK1 O15530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977831 0.99 PDK2 (0.43) PDK2CYP11B1CYP11B2CYP2A6CYP3A4
SCHEMBL15977588 0.97 PDK2 (0.44) PDK2CYP11B1CYP11B2CYP2A6CYP3A4
SCHEMBL15977516 0.96 PDK2 (0.45) PDK2CYP11B1CYP11B2CYP2A6CYP3A4
SCHEMBL15977926 0.93 PDK2 (0.46) PDK2CYP11B1CYP11B2CYP2A6CYP3A4
SCHEMBL15977744 0.92 PDK2 (0.38) PDK2CYP11B1CYP11B2PIK3CA
SCHEMBL20176484 0.91 PDK2 (0.40) PDK2CYP11B1CYP11B2CYP2A6CYP3A4
SCHEMBL15977858 0.91 PDK2 (0.49) PDK2CYP11B1CYP11B2CYP3A4DHODH
SCHEMBL15977928 0.90 PDK2 (0.39) PDK2CYP11B1CYP11B2DHODHPIK3CA
SCHEMBL26161150 0.90 PDK2 (0.39) PDK2CYP11B1CYP11B2CYP2A6CYP3A4
SCHEMBL15977821 0.90 PDK2 (0.48) PDK2CYP11B1CYP11B2CYP2A6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 PDK2 924/4885CYP11B1 1241/4885CYP11B2 1585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.