SCHEMBL15977928

SCHEMBL15977928

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(-c4c5ccccc5c(-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)c5cc(-c6ccc(-c7ccncc7)cn6)ccc45)cc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.39
PIK3CA P42336 2/20 0.34
IMPDH2 P12268 1/20 0.33
ALOX5AP P20292 3/20 0.32
FEN1 P39748 3/20 0.32
MAPK10 P53779 1/20 0.32
NTRK1 P04629 1/20 0.31
KDR P35968 1/20 0.31
PDPK1 O15530 1/20 0.31
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
DHODH Q02127 1/20 0.30
ACVR1 Q04771 1/20 0.30
MKNK1 Q9BUB5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977744 0.98 PDK2 (0.38) PDK2PIK3CAIMPDH2ALOX5APFEN1
SCHEMBL15977538 0.94 PDK2 (0.42) PDK2PIK3CAIMPDH2ALOX5APFEN1
SCHEMBL15977831 0.91 PDK2 (0.43) PDK2PIK3CAPDPK1CYP11B1CYP11B2
SCHEMBL15977747 0.90 PDK2 (0.47) PDK2PIK3CAIMPDH2DHODHMKNK1
SCHEMBL15977609 0.90 PDK2 (0.43) PDK2PIK3CAPDPK1CYP11B1CYP11B2
SCHEMBL26161337 0.88 PDK2 (0.42) PDK2PIK3CAIMPDH2MAPK10NTRK1
SCHEMBL26161340 0.88 PDK2 (0.42) PDK2PIK3CAIMPDH2MAPK10NTRK1
SCHEMBL15977823 0.88 PDK2 (0.44) PDK2ALOX5APFEN1KDRDHODH
SCHEMBL15977516 0.88 PDK2 (0.45) PDK2PIK3CAMAPK10CYP11B1CYP11B2
SCHEMBL15977588 0.87 PDK2 (0.44) PDK2PIK3CAMAPK10CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 PDK2 924/4885PIK3CA 2722/4885IMPDH2 3647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.