SCHEMBL15977697

SCHEMBL15977697

c1ccc(-c2ccc3c(-c4ccc(-c5cnc6ccccc6c5)cc4)c4ccccc4c(-c4ccc(-c5cnc6ccccc6c5)cc4)c3c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 4/20 0.59
PIK3CA P42336 4/20 0.59
MTOR P42345 3/20 0.59
PIK3CB P42338 2/20 0.59
PIK3CG P48736 2/20 0.59
PDGFRB P09619 4/20 0.54
PDGFRA P16234 4/20 0.54
BIRC5 O15392 1/20 0.54
CYP2A6 P11509 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
PRMT5 O14744 1/20 0.48
WDR77 Q9BQA1 1/20 0.48
MAP4K4 O95819 1/20 0.48
CSNK1G2 P78368 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48
MKNK2 Q9HBH9 1/20 0.48
MAP4K5 Q9Y4K4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29662082 0.91 BIRC5 (0.57) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL17836849 0.91 BIRC5 (0.57) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL13004545 0.91 PDGFRB (0.56) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL17246769 0.90 PDGFRB (0.53) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL19009471 0.90 PIK3CD (0.52) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL19008525 0.88 PIK3CA (0.52) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL24662776 0.88 CYP2A6 (0.56) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL13979077 0.88 PDGFRB (0.59) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL13820651 0.87 PIK3CD (0.47) PIK3CDPIK3CAMTORPIK3CBPIK3CG
SCHEMBL13820726 0.87 PIK3CD (0.47) PIK3CDPIK3CAMTORPIK3CBPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 PIK3CD 3449/4885PIK3CA 2722/4885MTOR 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.