SCHEMBL15977811

SCHEMBL15977811

c1ccc(-c2ccccc2-c2c3ccccc3c(-c3ccccc3-c3ccccc3)c3cc(-c4ccc(-c5ccccn5)cn4)ccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.43
HPGDS O60760 1/20 0.42
CYP2A6 P11509 1/20 0.42
KDR P35968 1/20 0.41
CHEK2 O96017 1/20 0.41
PRMT5 O14744 2/20 0.40
WDR77 Q9BQA1 1/20 0.40
TGFBR1 P36897 1/20 0.40
AXL P30530 2/20 0.39
PDK2 Q15119 1/20 0.38
METAP2 P50579 1/20 0.38
GRM5 P41594 1/20 0.38
CNR2 P34972 1/20 0.37
CDK8 P49336 1/20 0.37
TNIK Q9UKE5 1/20 0.37
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
WNT3A P56704 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977525 0.99 DHODH (0.42) DHODHHPGDSCYP2A6KDRCHEK2
SCHEMBL15977721 0.92 HPGDS (0.45) DHODHHPGDSCYP2A6KDRCHEK2
SCHEMBL15977812 0.91 HPGDS (0.44) DHODHHPGDSCYP2A6KDRCHEK2
SCHEMBL15977596 0.88 CYP2A6 (0.45) DHODHHPGDSCYP2A6KDRCHEK2
SCHEMBL15977565 0.88 DHODH (0.46) DHODHCYP2A6KDRPRMT5WDR77
SCHEMBL10030108 0.88 CYP2A6 (0.47) DHODHHPGDSCYP2A6KDRCHEK2
SCHEMBL10030102 0.86 CYP2A6 (0.46) DHODHHPGDSCYP2A6KDRCHEK2
SCHEMBL15977534 0.86 CYP11B1 (0.44) DHODHCYP2A6PDK2PIM1PIM3
SCHEMBL15977930 0.86 PIK3CA (0.46) DHODHKDRAXLCDK8TNIK
SCHEMBL15977833 0.86 PIK3CA (0.46) DHODHKDRAXLCDK8TNIK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 DHODH 3858/4885HPGDS 4636/4885CYP2A6 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.