Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.76 |
| ▸ | ST3GAL1 | Q11201 | 2/20 | 0.76 |
| ▸ | ST3GAL3 | Q11203 | 2/20 | 0.76 |
| ▸ | FUT6 | P51993 | 1/20 | 0.76 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | OSBP | P22059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351854 | 0.88 | ST6GAL1 (0.61) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL29711449 | 0.86 | ST6GAL1 (1.00) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL16406505 | 0.66 | ST6GAL1 (0.51) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL30753545 | 0.61 | ST6GAL1 (0.66) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL8143360 | 0.58 | ST6GAL1 (0.42) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL16408426 | 0.56 | ST6GAL1 (0.41) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL16406480 | 0.56 | ALOX5 (0.44) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL30075081 | 0.56 | ALOX5 (0.44) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL16406482 | 0.56 | ST6GAL1 (0.41) | ST6GAL1ST3GAL1ST3GAL3FUT6FUT5 | |
| SCHEMBL18789464 | 0.52 | ALOX15 (0.41) | ST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | WEE1, WEE2, NOTUM | ST6GAL1 2019/4885ST3GAL1 3686/4885ST3GAL3 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.