SCHEMBL15979306

SCHEMBL15979306

Cc1cnc(Oc2ccc(OC(C)C(=O)O)cc2)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.48
CYP2C9 P11712 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47
APEX1 P27695 1/20 0.47
MAP4K4 O95819 2/20 0.46
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP1A2 P05177 1/20 0.44
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
CYP2C19 P33261 1/20 0.44
ACACB O00763 1/20 0.44
LIPE Q05469 2/20 0.44
PPARG P37231 1/20 0.43
SCN9A Q15858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14769734 0.90 L3MBTL1 (0.54) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
SCHEMBL14769736 0.90 L3MBTL1 (0.54) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
SCHEMBL8689394 0.89 L3MBTL1 (0.53) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
Pyriphenop SCHEMBL134252 0.88 L3MBTL1 (0.67) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
Pyriphenop SCHEMBL29419117 0.88 L3MBTL1 (0.67) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
Pyriphenop SCHEMBL8081008 0.88 L3MBTL1 (0.67) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
SCHEMBL15449627 0.88 L3MBTL1 (0.61) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
Pyriphenop SCHEMBL10727244 0.87 L3MBTL1 (0.65) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
Pyriphenop SCHEMBL10824511 0.87 L3MBTL1 (0.65) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA
Pyriphenop SCHEMBL11012717 0.87 L3MBTL1 (0.65) L3MBTL1TDP1CYP2C9SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180007899-A1 HERBICIDAL COMPOSITIONS COMPRISING OXYFLUORFEN AND HALOXYFOP DOW AGROSCIENCES LLC 2018-01-11 US disclosed
US-9717244-B2 Methods of weed control in pineapple DOW AGROSCIENCES LLC (US) 2017-08-01 US disclosed
US-9717244-B2 Methods of weed control in pineapple DOW AGROSCIENCES LLC (US) 2017-08-01 US disclosed
US-20170164613-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF HALOXYFOP AND ALS INHIBITOR HERBICIDES CORTEVA AGRISCIENCE LLC 2017-06-15 US disclosed
US-9609867-B2 Synergistic weed control from applications of haloxyfop and ALS inhibitor herbicides DOW AGROSCIENCES LLC (US) 2017-04-04 US disclosed
US-20150305335-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF HALOXYFOP AND ALS INHIBITOR HERBICIDES CORTEVA AGRISCIENCE LLC 2015-10-29 US disclosed
US-20140323298-A1 HERBICIDAL COMPOSITIONS COMPRISING OXYFLUORFEN AND HALOXYFOP DOW AGROSCIENCES LLC (US) 2014-10-30 US disclosed
US-20140243198-A1 METHODS OF WEED CONTROL IN PINEAPPLE DOW AGROSCIENCES LLC (US) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243198-A1 METHODS OF WEED CONTROL IN PINEAPPLE NPEPPS, NOTUM, DNPEP L3MBTL1 785/4885TDP1 1849/4885CYP2C9 701/4885
US-20140323298-A1 HERBICIDAL COMPOSITIONS COMPRISING OXYFLUORFEN AND HALOXYFOP CYP4F3, PHF2, ASF1A L3MBTL1 2589/4885TDP1 709/4885CYP2C9 272/4885
US-20170164613-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF HALOXYFOP AND ALS INHIBITOR HERBICIDES NOTUM, HACL2, SOD1 L3MBTL1 267/4885TDP1 116/4885CYP2C9 734/4885
US-20150305335-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF HALOXYFOP AND ALS INHIBITOR HERBICIDES NOTUM, HACL2, SOD1 L3MBTL1 267/4885TDP1 116/4885CYP2C9 734/4885
US-20180007899-A1 HERBICIDAL COMPOSITIONS COMPRISING OXYFLUORFEN AND HALOXYFOP CYP4F3, PHF2, ASF1A L3MBTL1 2589/4885TDP1 709/4885CYP2C9 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.