Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848965 | 0.91 | THRB (0.33) | ALDH1A1CNR1CNR2THRBUSP2 | |
| SCHEMBL15980571 | 0.87 | ALDH1A1 (0.30) | ALDH1A1CNR1CNR2 | |
| SCHEMBL16656647 | 0.84 | ALDH1A1 (0.33) | ALDH1A1CNR1CNR2USP2 | |
| SCHEMBL29017451 | 0.84 | ALDH1A1 (0.36) | ALDH1A1CNR1CNR2THRBUSP2 | |
| SCHEMBL304955 | 0.84 | ALDH1A1 (0.36) | ALDH1A1CNR1CNR2THRBUSP2 | |
| SCHEMBL14848972 | 0.82 | ALDH1A1 (0.35) | ALDH1A1CNR1CNR2USP2 | |
| SCHEMBL337832 | 0.81 | — | — | |
| Ethylene SCHEMBL23276997 | 0.80 | ALDH1A1 (0.33) | ALDH1A1CNR1CNR2THRBUSP2 | |
| SCHEMBL5765642 | 0.78 | USP2 (0.47) | ALDH1A1CNR1CNR2USP2 | |
| SCHEMBL9446799 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CNR1CNR2THRBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140241988-A1 | METHODS AND COMPOSITIONS FOR TREATING ATRIAL FIBRILLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140241988-A1 | METHODS AND COMPOSITIONS FOR TREATING ATRIAL FIBRILLATION | RYR2, FABP3, CA3 | ALDH1A1 439/4885CNR1 888/4885CNR2 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.