SCHEMBL159808

SCHEMBL159808

COC(=O)C(O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.57
TK2 O00142 4/20 0.53
SLC28A1 O00337 1/20 0.49
SLC28A2 O43868 1/20 0.49
SLC29A1 Q99808 1/20 0.49
SLC28A3 Q9HAS3 1/20 0.49
DNPH1 O43598 1/20 0.46
P2RY2 P41231 1/20 0.46
P2RY6 Q15077 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18852615 1.00 PYGM (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL15810677 1.00 PYGM (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL16805348 1.00 PYGM (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18740741 0.91 TK2 (0.49) PYGMTK2
SCHEMBL16807689 0.91 PYGM (0.59) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL29188121 0.88 PYGM (0.53) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18503568 0.88 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL40819 0.88 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18512919 0.88 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18512917 0.88 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118176209-A Treatment involving non-immunogenic RNA and PD-1 axis binding antagonists for antigen vaccination 生物技术公司 2024-06-11 CN claimed
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 EP claimed
EP-4306643-A2 PLASMID CONTAINING A SEQUENCE ENCODING AN MRNA WITH A SEGMENTED POLY(A) TAIL ethris GmbH (DE) 2024-01-17 EP claimed
CN-117413065-A Constructs, methods and uses for the preparation of circular RNAs 上海环码生物医药有限公司 2024-01-16 CN claimed
EP-3656872-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY Novartis AG (CH) 2020-05-27 EP claimed
EP-3387150-B1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY NOVARTIS AG (CH) 2019-10-02 EP claimed
EP-3387150-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY Novartis AG (CH) 2018-10-17 EP claimed
US-9719084-B2 Co-transcriptional assembly of modified RNA nanoparticles THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2017-08-01 US claimed
WO-2017098468-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY NOVARTIS AG (CH) 2017-06-15 WO claimed
US-20150203842-A1 CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 2015-07-23 US claimed
WO-2014039809-A2 CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2014-03-13 WO claimed
EP-2578685-A2 RNA containing modified nucleosides and methods of use thereof The Trustees of The University of Pennsylvania (US) 2013-04-10 EP claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
CN-120129702-A RNA compositions targeting claudin-18.2 生物技术公司 2025-06-10 CN disclosed
CN-120092014-A RNA constructs and uses thereof 生物技术欧洲股份公司 2025-06-03 CN disclosed
CN-119968210-A RNA for preventing or treating tuberculosis 生物技术公司 2025-05-09 CN disclosed
WO-2007024708-A2 RNA CONTAINING MODIFIED NUCLEOSIDES AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-03-01 WO disclosed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US disclosed
EP-1221615-A2 S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy ORIDIGM CORPORATION (US) 2002-07-10 EP disclosed
US-6020139-A S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy ORIDIGM CORPORATION (US) 2000-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR PYGM 598/4885TK2 3708/4885SLC28A1 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.