Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134449 | 0.82 | DTYMK (0.64) | DTYMKAKR1C2AKR1C1CASP6TSHR | |
| SCHEMBL267752 | 0.82 | DTYMK (0.64) | DTYMKAKR1C2AKR1C1CASP6TSHR | |
| SCHEMBL31283743 | 0.82 | DTYMK (0.64) | DTYMKAKR1C2AKR1C1CASP6TSHR | |
| SCHEMBL10831554 | 0.80 | DTYMK (0.62) | DTYMKAKR1C2AKR1C1CASP6TSHR | |
| SCHEMBL6397073 | 0.80 | DTYMK (0.62) | DTYMKAKR1C2AKR1C1CASP6TSHR | |
| SCHEMBL31431111 | 0.80 | DTYMK (0.57) | DTYMKCASP6TSHRMEN1KMT2A | |
| SCHEMBL2772094 | 0.80 | DTYMK (0.57) | DTYMKCASP6TSHRMEN1KMT2A | |
| SCHEMBL15988990 | 0.78 | CASP6 (0.54) | CASP6TSHR | |
| SCHEMBL11282911 | 0.76 | MEN1 (0.54) | DTYMKAKR1C2AKR1C1CASP6BACE1 | |
| SCHEMBL15989079 | 0.73 | TP53 (0.49) | FFAR1NPSR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| EP-2958889-B1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | SCRIPPS RESEARCH INST (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| WO-2014131023-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | TLR2, TLR4, TLR1 | DTYMK 2591/4885HNF4A 3925/4885AKR1C2 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.