Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599685 | 0.98 | ALDH1A1 (0.54) | ALDH1A1LMNAFGFR1MEN1KMT2A | |
| SCHEMBL1599288 | 0.86 | FYN (0.57) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1599724 | 0.85 | PRKDC (0.57) | ALDH1A1MEN1KMT2AHIF1AUSP2 | |
| SCHEMBL1600775 | 0.85 | ADRB1 (0.56) | LMNAMAPT | |
| SCHEMBL10408441 | 0.84 | FGFR1 (0.59) | ALDH1A1LMNAFGFR1MEN1KMT2A | |
| SCHEMBL7303075 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2AHIF1A | |
| SCHEMBL1599674 | 0.82 | PTPN7 (0.51) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL25656899 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAFGFR1MEN1KMT2A | |
| SCHEMBL28860292 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNAMEN1KMT2AHIF1A | |
| SCHEMBL1599268 | 0.81 | MAPT (0.56) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870085-B1 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| US-7651536-B2 | Composition for dyeing of keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, at least one oxidation base chosen from para-phenylenediamine and para-tolylenediamine, and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | claimed |
| US-7651537-B2 | Composition for dyeing keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | claimed |
| US-20080016628-A1 | Composition for dyeing keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2008-01-24 | — | — | US | claimed |
| US-20080016627-A1 | Composition for dyeing of keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, at least one oxidation base chosen from para-phenylenediamine and para-tolylenediamine, and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2008-01-24 | — | — | US | claimed |
| EP-1870084-A2 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | claimed |
| EP-1870085-A2 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | claimed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| EP-1870085-B1 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | disclosed |
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | disclosed |
| EP-1927377-B1 | Dye composition of acidic pH comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, a para- phenylenediamine, a meta-aminophenol and an oxidizing agent | OREAL (FR) | 2012-12-26 | — | — | EP | disclosed |
| CN-101091691-B | Keratin fibre dyeing composition containing 2, 3-diamino-6, 7-dihydro-1H, 5H-pyrazolo [1,2-a ] pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and substituted meta-aminophenol | OREAL | 2012-05-02 | — | — | CN | disclosed |
| EP-1870083-A2 | Process for the predictable dyeing of keratinous fibres by application of a composition comprising a diamino-N,N-dihydropyrazolone derivative and of a fundamental or golden-highlights composition | L'Oréal (FR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1870085-A2 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | disclosed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | ALDH1A1 8/4885LMNA 2903/4885FGFR1 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.