Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632526 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1599791 | 0.84 | TYR (0.41) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1600055 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL2472187 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1598898 | 0.81 | TYR (0.42) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL9658931 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1537962 | 0.77 | S100B (0.56) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL3825706 | 0.76 | HSPA5 (0.53) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL15488864 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1598641 | 0.75 | MAPT (0.41) | ALDH1A1CYP3A4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-1870085-B1 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| CN-101229106-B | Dye composition of acidic ph comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, a para- phenylenediamine, a meta-aminophenol and an oxidizing agent | OREAL | 2013-04-10 | — | — | CN | claimed |
| CN-101091691-B | Keratin fibre dyeing composition containing 2, 3-diamino-6, 7-dihydro-1H, 5H-pyrazolo [1,2-a ] pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and substituted meta-aminophenol | OREAL | 2012-05-02 | — | — | CN | claimed |
| US-7651536-B2 | Composition for dyeing of keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, at least one oxidation base chosen from para-phenylenediamine and para-tolylenediamine, and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | claimed |
| US-7651537-B2 | Composition for dyeing keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | claimed |
| US-20080016627-A1 | Composition for dyeing of keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, at least one oxidation base chosen from para-phenylenediamine and para-tolylenediamine, and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2008-01-24 | — | — | US | claimed |
| US-20080016628-A1 | Composition for dyeing keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2008-01-24 | — | — | US | claimed |
| CN-101108157-A | Composition for dyeing of keratin fibers | OREAL (FR) | 2008-01-23 | — | — | CN | claimed |
| EP-1870084-A2 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | claimed |
| EP-1870085-A2 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | claimed |
| CN-101091691-A | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | OREAL (FR) | 2007-12-26 | — | — | CN | claimed |
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | disclosed |
| EP-1870085-B1 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | disclosed |
| CN-101229106-B | Dye composition of acidic ph comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, a para- phenylenediamine, a meta-aminophenol and an oxidizing agent | OREAL | 2013-04-10 | — | — | CN | disclosed |
| EP-1927377-B1 | Dye composition of acidic pH comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, a para- phenylenediamine, a meta-aminophenol and an oxidizing agent | OREAL (FR) | 2012-12-26 | — | — | EP | disclosed |
| EP-1870083-A2 | Process for the predictable dyeing of keratinous fibres by application of a composition comprising a diamino-N,N-dihydropyrazolone derivative and of a fundamental or golden-highlights composition | L'Oréal (FR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1870084-A2 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1870085-A2 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | L'Oréal (FR) | 2007-12-26 | — | — | EP | disclosed |
| CN-101091691-A | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | OREAL (FR) | 2007-12-26 | — | — | CN | disclosed |