Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004329 | 0.93 | MAPK1 (0.54) | SMN1; SMN2MAPK1USP2KMT2AALDH1A1 | |
| SCHEMBL16004257 | 0.80 | PKM (0.50) | MAPK1KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL16004327 | 0.80 | PKM (0.51) | SMN1; SMN2USP2POLBKMT2AALDH1A1 | |
| SCHEMBL16004019 | 0.78 | PKM (0.44) | SMN1; SMN2MAPK1POLBKMT2AALDH1A1 | |
| SCHEMBL16004012 | 0.78 | NPC1 (0.41) | MAPK1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL16004260 | 0.75 | CCR3 (0.50) | MAPK1USP2KMT2AALDH1A1LMNA | |
| SCHEMBL16004333 | 0.74 | PKM (0.47) | SMN1; SMN2MAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL16004330 | 0.73 | PKM (0.46) | SMN1; SMN2USP2KMT2AALDH1A1LMNA | |
| SCHEMBL16004229 | 0.72 | PKM (0.46) | MAPK1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL16004107 | 0.72 | PKM (0.45) | SMN1; SMN2KMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |