Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200591 | 0.86 | MAPT (0.34) | PSMB5ALDH1A1 | |
| SCHEMBL12200598 | 0.86 | MAPT (0.34) | PSMB5ALDH1A1 | |
| SCHEMBL12225491 | 0.86 | MAPT (0.34) | PSMB5ALDH1A1 | |
| SCHEMBL14184587 | 0.82 | MCL1 (0.38) | — | |
| SCHEMBL22300364 | 0.81 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL17617892 | 0.79 | MCL1 (0.34) | — | |
| SCHEMBL19646651 | 0.78 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL13807013 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL15235435 | 0.78 | CYP2D6 (0.30) | — | |
| SCHEMBL13474987 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014131122-A1 | FORMULATIONS OF GROWTH HORMONE RELEASING FACTOR (GRF) MOLECULES WITH IMPROVED STABILITY | THERATECHNOLOGIES, INC. (CA) | 2014-09-04 | — | — | WO | disclosed |