Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29335435 | 0.82 | MMP2 (0.36) | — | |
| SCHEMBL13035653 | 0.82 | — | — | |
| SCHEMBL27475433 | 0.82 | MCL1 (0.32) | MCL1LMNAATM | |
| SCHEMBL24379707 | 0.82 | — | — | |
| SCHEMBL13258521 | 0.81 | MMP2 (0.40) | MCL1LMNAATM | |
| SCHEMBL277484 | 0.81 | ATM (0.37) | MCL1LMNAATM | |
| SCHEMBL14184587 | 0.80 | MCL1 (0.38) | MCL1 | |
| SCHEMBL13525020 | 0.80 | MEN1 (0.38) | LMNA | |
| SCHEMBL13474987 | 0.80 | ALDH1A1 (0.43) | — | |
| SCHEMBL12157037 | 0.80 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238459-A1 | Granzyme-Activatable Membrane-Interacting Peptides and Methods of Use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-07-18 | — | — | US | disclosed |
| US-11712483-B2 | Activatable membrane-interacting peptides and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-01 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-9789209-B2 | Activatable membrane-interacting peptides and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, BERKE (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160082131-A1 | Activatable Membrane-Interacting Peptides and Methods of Use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712483-B2 | Activatable membrane-interacting peptides and methods of use | ANXA5, PLA2G2A, F13B | MCL1 320/4885LMNA 108/4885ATM 3968/4885 |
| US-20240238459-A1 | Granzyme-Activatable Membrane-Interacting Peptides and Methods of Use | GZMB, PRF1, PLA2G2A | MCL1 454/4885LMNA 498/4885ATM 4408/4885 |
| US-20160082131-A1 | Activatable Membrane-Interacting Peptides and Methods of Use | ANXA5, PLA2G2A, F13B | MCL1 320/4885LMNA 108/4885ATM 3968/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | MCL1 2299/4885LMNA 826/4885ATM 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.