Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004706 | 0.96 | SMN1; SMN2 (0.46) | SMN1; SMN2USP2MAPTLMNAALDH1A1 | |
| SCHEMBL13386221 | 0.94 | SMN1; SMN2 (0.38) | SMN1; SMN2USP2MAPTLMNAALDH1A1 | |
| Iodide SCHEMBL13386311 | 0.93 | SMN1; SMN2 (0.37) | SMN1; SMN2USP2MAPTLMNAALDH1A1 | |
| SCHEMBL15875889 | 0.90 | MAPT (0.46) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 | |
| SCHEMBL15875834 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2USP2MAPTLMNAALDH1A1 | |
| SCHEMBL2587174 | 0.84 | GPR119 (0.46) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 | |
| Iodide SCHEMBL9932164 | 0.83 | GPR119 (0.45) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 | |
| SCHEMBL15875933 | 0.82 | MAPT (0.40) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 | |
| SCHEMBL13386335 | 0.82 | MAPT (0.43) | SMN1; SMN2USP2MAPTLMNAALDH1A1 | |
| Iodide SCHEMBL13386315 | 0.80 | PDK2 (0.40) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828986-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-09-09 | — | — | US | claimed |