Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587174 | 0.94 | GPR119 (0.46) | MAPTALDH1A1LMNAGPR119PDK2 | |
| SCHEMBL16004706 | 0.94 | SMN1; SMN2 (0.46) | MAPTALDH1A1LMNAGPR119PDK2 | |
| Iodide SCHEMBL9932164 | 0.93 | GPR119 (0.45) | MAPTALDH1A1LMNAGPR119PDK2 | |
| SCHEMBL15875933 | 0.92 | MAPT (0.40) | MAPTALDH1A1LMNAGPR119PDK2 | |
| SCHEMBL16004682 | 0.90 | SMN1; SMN2 (0.43) | MAPTALDH1A1LMNAGPR119PDK2 | |
| SCHEMBL15875834 | 0.87 | SMN1; SMN2 (0.40) | MAPTALDH1A1LMNAGPR119MEN1 | |
| SCHEMBL15875911 | 0.85 | ALDH1A1 (0.36) | MAPTALDH1A1LMNAGPR119PDK2 | |
| SCHEMBL13386221 | 0.84 | SMN1; SMN2 (0.38) | MAPTALDH1A1LMNAGPR119PDK2 | |
| Iodide SCHEMBL9933682 | 0.84 | GPR119 (0.42) | MAPTALDH1A1LMNAGPR119PDK2 | |
| Iodide SCHEMBL13386311 | 0.84 | SMN1; SMN2 (0.37) | MAPTALDH1A1LMNAGPR119PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785434-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-07-22 | — | — | US | claimed |