Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9932164 | 0.99 | GPR119 (0.45) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL15875889 | 0.94 | MAPT (0.46) | GPR119MAPTALDH1A1LMNAPDK2 | |
| Iodide SCHEMBL9933682 | 0.90 | GPR119 (0.42) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL16004706 | 0.88 | SMN1; SMN2 (0.46) | GPR119MAPTALDH1A1LMNAPDK2 | |
| Iodide SCHEMBL13386315 | 0.87 | PDK2 (0.40) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL15875933 | 0.86 | MAPT (0.40) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL2592117 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1PDK2MEN1KMT2A | |
| SCHEMBL16004682 | 0.84 | SMN1; SMN2 (0.43) | GPR119MAPTALDH1A1LMNAPDK2 | |
| Iodide SCHEMBL9932942 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1PDK2MEN1KMT2A | |
| SCHEMBL15875834 | 0.82 | SMN1; SMN2 (0.40) | GPR119MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585073-A1 | ANTIVIRAL COMPOUNDS | Prostetta Antiviral Inc. (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011137447-A1 | ANTIVIRAL COMPOUNDS | PROSTETTA ANTIVIRAL INC. (US) | 2011-11-03 | — | — | WO | disclosed |