Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.77 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.75 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733238 | 0.87 | PIK3CG (0.77) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL30387397 | 0.86 | PIK3CG (1.00) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL24846337 | 0.83 | PIK3CG (0.71) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL734037 | 0.81 | PIK3CG (0.76) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL7041562 | 0.81 | PIK3CG (0.68) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL734881 | 0.81 | PIK3CG (0.68) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL733967 | 0.80 | PIK3CG (0.76) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL733439 | 0.79 | PIK3CG (0.66) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL788778 | 0.79 | PIK3CD (1.00) | PIK3CGPOLBRECQLPIK3CDPIK3CB | |
| SCHEMBL733234 | 0.79 | PIK3CG (0.65) | PIK3CGPOLBRECQLPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2018-05-03 | — | — | US | disclosed |
| US-9834560-B2 | Compounds | RESPIVERT LTD. (GB) | 2017-12-05 | — | — | US | disclosed |
| US-20160264583-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2016-09-15 | — | — | US | disclosed |
| US-9321773-B2 | Compounds | Respivert, Ltd. (GB) | 2016-04-26 | — | — | US | disclosed |
| US-20140249164-A1 | COMPOUNDS | RESPIVERT LTD (GB) | 2014-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264583-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | PIK3CG 3708/4885POLB 1044/4885RECQL 1294/4885 |
| US-20140249164-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | PIK3CG 3708/4885POLB 1044/4885RECQL 1294/4885 |
| US-20180118754-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | PIK3CG 3708/4885POLB 1044/4885RECQL 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.