Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041562 | 0.90 | PIK3CG (0.68) | PIK3CGPIK3CDPIK3CBPOLBRECQL | |
| SCHEMBL734675 | 0.86 | PIK3CG (0.61) | PIK3CGPIK3CDPIK3CBPOLBRECQL | |
| SCHEMBL24846340 | 0.83 | POLB (0.54) | PIK3CGPIK3CDPIK3CBPOLBRECQL | |
| SCHEMBL16004753 | 0.83 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPOLBRECQL | |
| SCHEMBL734881 | 0.80 | PIK3CG (0.68) | PIK3CGPIK3CDPIK3CBPOLBRECQL | |
| SCHEMBL24846338 | 0.78 | ALDH1A1 (0.75) | PIK3CGPOLBRECQLPIN1ALDH1A1 | |
| SCHEMBL734311 | 0.77 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3CBPIK3R1 | |
| SCHEMBL7174836 | 0.77 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3CBPIK3R1 | |
| SCHEMBL734001 | 0.77 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3CBPOLBRECQL | |
| SCHEMBL733666 | 0.77 | PIK3CG (0.55) | PIK3CGPIK3CDPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ATEN PORUS LIFESCIENCES PVT. LTD. (IN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ENPP1, ENPP3, PNP | PIK3CG 802/4885PIK3CD 630/4885PIK3CB 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.