Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641540 | 0.84 | POLB (0.43) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL4641645 | 0.83 | ERN1 (0.50) | ERN1ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL16005543 | 0.83 | MEN1 (0.52) | ERN1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL16005123 | 0.80 | ERN1 (0.50) | ERN1ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL4643215 | 0.80 | HSD17B10 (0.43) | ALDH1A1CYP1A2MEN1KMT2ATDP1 | |
| SCHEMBL31715172 | 0.76 | CYP1A2 (0.42) | ERN1ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL5458569 | 0.74 | ALDH1A1 (0.50) | ERN1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2300015 | 0.73 | ERN1 (0.46) | ERN1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL11477102 | 0.73 | CA1 (0.46) | ERN1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL16005078 | 0.72 | THRA (0.42) | ERN1ALDH1A1CYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774914-B1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | UNIV NANJING MEDICAL (CN) | 2017-12-06 | — | — | EP | disclosed |
| US-9481636-B2 | N-benzylaniline derivative and uses thereof | NANJING MEDICAL UNIVERSITY (CN) | 2016-11-01 | — | — | US | disclosed |
| CN-103086908-B | N-benzylaniline derivatives and application thereof | UNIV NANJING MEDICAL | 2015-05-13 | — | — | CN | disclosed |
| US-20140303248-A1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | Neurodawn Pharmaceutical Co., Ltd. (CN) | 2014-10-09 | — | — | US | disclosed |
| EP-2774914-A1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | Nanjing Medical University (CN) | 2014-09-10 | — | — | EP | disclosed |
| CN-103086908-A | N-benzylaniline derivatives and application thereof | UNIV NANJING MEDICAL | 2013-05-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303248-A1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | NLN, INA, TRPV1 | ERN1 1346/4885ALDH1A1 1015/4885CYP1A2 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.