Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005543 | 0.89 | MEN1 (0.52) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL2300015 | 0.76 | ERN1 (0.46) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| Potassium Ion SCHEMBL8193405 | 0.75 | ERN1 (0.49) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL16005190 | 0.74 | ERN1 (0.41) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL4645395 | 0.74 | ABCB11 (0.49) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL27957060 | 0.72 | KMT2A (0.44) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL6413771 | 0.69 | ERN1 (0.53) | ALDH1A1KMT2AMEN1TDP1ERN1 | |
| SCHEMBL18871612 | 0.69 | ABCB11 (0.45) | ALDH1A1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL31551028 | 0.69 | ERN1 (0.53) | ALDH1A1KMT2AMEN1TDP1ERN1 | |
| SCHEMBL18313858 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | ALDH1A1 627/4885KMT2A 4167/4885RAB9A 1141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.