SCHEMBL16005297

SCHEMBL16005297

COC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)c1ccc(C)cc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
RAB9A P51151 2/20 0.58
GAA P10253 1/20 0.58
ALDH1A1 P00352 4/20 0.57
LMNA P02545 2/20 0.57
GLA P06280 1/20 0.57
SLC6A9 P48067 1/20 0.54
POLB P06746 2/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
THRB P10828 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
HSD17B10 Q99714 1/20 0.51
PLAU P00749 1/20 0.50
PLAT P00750 1/20 0.50
NPC1 O15118 1/20 0.50
OPRK1 P41145 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26820570 0.87 GAA (0.73) ATML3MBTL1RAB9AGAAALDH1A1
SCHEMBL4175147 0.87 GAA (0.73) ATML3MBTL1RAB9AGAAALDH1A1
SCHEMBL17433498 0.84 GAA (0.51) ATML3MBTL1RAB9AGAAALDH1A1
SCHEMBL23923341 0.82 KMT2A (0.47) ATML3MBTL1RAB9ALMNASLC6A9
SCHEMBL23923343 0.82 KMT2A (0.47) ATML3MBTL1RAB9ALMNASLC6A9
SCHEMBL14816081 0.81 ATM (0.69) ATML3MBTL1ALDH1A1LMNAPOLB
SCHEMBL14205009 0.81 ATM (0.69) ATML3MBTL1ALDH1A1LMNAPOLB
SCHEMBL11022457 0.81 FPR2 (0.60) RAB9AALDH1A1SLC6A9POLBKMT2A
SCHEMBL11025321 0.80 RAB9A (0.54) L3MBTL1RAB9AGAAALDH1A1LMNA
SCHEMBL28914294 0.80 ATM (0.60) ATML3MBTL1RAB9AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2774930-A1 Metallocene compounds and labeled molecules comprising the same for in vivo imaging. Aptenia S.R.L. (IT) 2014-09-10 EP disclosed