Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441850 | 0.85 | ALDH1A1 (0.37) | TDP1SMN1; SMN2 | |
| SCHEMBL14192720 | 0.80 | KMT2A (0.34) | TDP1CA1CA2SMN1; SMN2ANPEP | |
| SCHEMBL1752393 | 0.80 | TSHR (0.37) | CA1CA2SMN1; SMN2ANPEP | |
| SCHEMBL3249360 | 0.80 | ALDH1A1 (0.36) | TDP1CA1CA2SMN1; SMN2ANPEP | |
| SCHEMBL15268831 | 0.79 | — | — | |
| SCHEMBL23175627 | 0.79 | GAA (0.45) | TDP1SMN1; SMN2 | |
| SCHEMBL11670845 | 0.77 | CA1 (0.38) | CA1CA2SMN1; SMN2ZDHHC7ANPEP | |
| SCHEMBL13548729 | 0.77 | ALDH1A1 (0.33) | SMN1; SMN2ANPEP | |
| SCHEMBL10526563 | 0.76 | CA1 (0.42) | TDP1CA1CA2SMN1; SMN2ZDHHC7 | |
| SCHEMBL13315130 | 0.76 | CA1 (0.32) | CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014131315-A1 | BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-09-04 | — | — | WO | disclosed |