Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493555 | 0.88 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16885017 | 0.85 | CSNK2A2 (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11694686 | 0.84 | EPHX1 (0.51) | NPC1RAB9ASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL9249492 | 0.84 | MEN1 (0.55) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| Allyl 2-Furoate SCHEMBL11521492 | 0.84 | ALDH1A1 (0.61) | NPC1RAB9ASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL15287341 | 0.84 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL11325853 | 0.83 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7116824 | 0.83 | TGM2 (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5073940 | 0.83 | TGM2 (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL114047 | 0.83 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3155 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991655-B1 | COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2024-04-10 | — | — | EP | claimed |
| US-11931332-B2 | Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2024-03-19 | — | — | US | claimed |
| CN-115677609-B | Method for cyclizing and cyanating allyl phenyl carbamate derivative | 湖北工业大学 | 2023-10-24 | — | — | CN | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-4204395-A1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISEASE | Bio-Pharm Solutions Co., Ltd. (KR) | 2023-07-05 | — | — | EP | claimed |
| CN-115677609-A | Method for self-cyclizing cyanation of phenyl allyl carbamate derivative | 湖北工业大学 | 2023-02-03 | — | — | CN | claimed |
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | claimed |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| EP-2968211-B1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO PHARM SOLUTIONS CO LTD (KR) | 2021-05-12 | — | — | EP | claimed |
| EP-0410900-B1 | Method for the preparation of methylene di(phenylurethane) | RHONE POULENC CHIMIE (FR) | 1995-03-15 | — | — | EP | claimed |
| EP-0406129-B1 | Method for the preparation of methylene di(phenylurethane) | RHONE POULENC CHIMIE (FR) | 1994-11-23 | — | — | EP | claimed |
| US-5206412-A | Reacting alkylphenylcarbamate with methylene bis(alkyl carbamate); acid catlayst | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1993-04-27 | — | — | US | claimed |
| US-5068391-A | Rearrangement of bis/N-carboalkoxyanilino/methane in the presence of hydrofluoric acid | RHONE-POULENC CHIMIE (FR) | 1991-11-26 | — | — | US | claimed |
| US-5066827-A | From ethyl N-phenylcarbamate and formaldehyde, trioxane, methylal or paraformaldehyde, hydrofluoric acid catalyst, intermediate for diphenylmethane diisocyanate | RHONE-POULENC CHIMIE (FR) | 1991-11-19 | — | — | US | claimed |
| US-4303794-A | Separation and recovery of 4,4'-methylene dimethyl diphenyldicarbamate | THE DOW CHEMICAL COMPANY (US) | 1981-12-01 | — | — | US | claimed |
| US-4292254-A | COSOLVENT, SOLVENT EXTRACTION, AQUEOUS ACID | ATLANTIC RICHFIELD COMPANY (US) | 1981-09-29 | — | — | US | claimed |
| US-4290968-A | REMOVAL OF AMINE BY-PRODUCTS WITH ION EXCHANGE RESINS | ATLANTIC RICHFIELD COMPANY (US) | 1981-09-22 | — | — | US | claimed |
| US-4287132-A | THE IMPROVED PROCESS WHEREIN THE POLYCARBAMATE IS DISTILLED, A POLAR SOLVENT IS ADDED TO THE RESIDUE, AND THE RESULTING SOLUTION IS CRYSTALLIZED | ATLANTIC RICHFIELD COMPANY (US) | 1981-09-01 | — | — | US | claimed |
| US-4029490-A | BENZYLTHIOLCARBAMATE | ISHIHARA SANGYO KAISHA LTD. (JA) | 1977-06-14 | — | — | US | claimed |